Expanding Frontiers in Autoimmune Encephalitis

Objective To characterize a case series of Colombian patients with autoimmune encephalitis (AE). Background AE is often an under-recognized entity and antibody testing not widely available in many developing countries. There lack population-based data on Colombia. Design/Methods We made comprehensive review the literature Additionally, we contacted researchers other tertiary care institutions Bogotá, Colombia to obtain information additional unpublished cases. Results 45 individuals were included antibodies identified 73.3% them. The most prevalent was NMDA followed by LGI-1. Clinical characteristics according specific similar those reported literature. Interestingly 1 patient had Zika virus (ZIKV) 4 months before LGI-1 AE, another developed immunodeficiency following related AE. A total 5 negative screen. no 7 patients. Conclusions clinical phenotypes our previously published. It important highlight novel infectious trigger postencephalitic immune mediated complication that, best knowledge, have been initial diagnostic approach can be based findings conventional tests, especially countries limited resources where accessible all clinicians.